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Research was conducted by the institute and its partners on various alcohol related issues.

In 2007, a literature review was conducted by the Medical Research Council (MRC) on behalf of Soul City. The review, Alcohol Use Literature Review, looked at levels and patterns of alcohol consumption in the country as well as global best practise on how to reduce levels of abuse. In 2009 a review on the legislation around alcohol consumption and regulation, Legal Literature Review, looked at how best to regulate and reduce alcohol consumption. Also in 2009 the Community Agency for Social Enquiry (CASE), conducted research on behalf of Soul City that looked at National and Provincial Government Spending and Revenue Related to Alcohol Abuse. In 2011 Soul City commissioned research on Marketing and Alcohol Consumption in South Africa.  The institute also commissioned the Wits University Centre for Applied Legal Studies (CALS) to review Alcohol in schools and the tertiary sector.